2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Aldehyde Oxidase (AO)

Aldehyde Oxidase (AO) (醛氧化酶)

Aldehyde Oxidase; AO

Aldehyde Oxidase is a soluble cytoplasmic molybdenum-containing enzyme that is mainly involved in the biotransformation of various drugs and xenobiotics. Aldehyde Oxidase has four isoforms (AOX1, AOX3, AOX3L1, and AOX4). Aldehyde Oxidase is mainly expressed by the liver, but is distributed widely in the lungs, kidneys, brain, and skin. Aldehyde Oxidase catalyzes oxidation and reduction reactions, among which the oxidation of aldehydes, nitro/nitroso compounds or N-heterocycles are more common. Aldehyde Oxidase affects drug metabolism, impacts drug interactions, and generates potential toxic metabolites. Aldehyde Oxidase could lead to liver damage (such as NAFLD), renal toxicity and amyotrophic lateral sclerosis (ALS)[1][2].

Aldehyde Oxidase (AO) 相关产品 (2):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-13735
    Quinacrine Inhibitor 98.20%
    Quinacrine (Acriquine) 是一种抗疟疾和抗癌剂。Quinacrine 还抑制人醛氧化酶 (aldehyde oxidase) (IC50: 3.3 μM)。Quinacrine 对核酸具有亲和力，并对固定细胞中的 DNA 和 RNA 染色 (Ex/Em: 436/525 nm)。
    Quinacrine
  • HY-19844
    ANA-975
    ANA975 是 TLR-7 激动剂 Isatoribine (HY-13655A) 的口服前药，5-amino-3-β -D-ribofuranosyl-3H-thiazolo[4,5-d]pyrimidin-2-one 衍生物。ANA975 通过酯酶水解和醛氧化酶氧化的联合机制转化为 Isatoribine。ANA975 可用于丙型肝炎病毒感染的研究。
    ANA-975
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z